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Methods in enzymology. v.252, Biothiols. Part B, Glutathione and thioredoxin, thiols in signal transduction and gene regulation

Methods in enzymology. v.252, Biothiols. Part B, Glutathione and thioredoxin, thiols in signal transduction and gene regulation

Packer, Lester

The critically acclaimed laboratory standard for forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerlyawaited, frequently consulted, and praised by researchers and reviewers alike. More than 250 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Key Features* Distribution, biosynthesis, metabolism, and transport of glutathione* Signal transduction and gene regulation* Thioredoxin and glutaredoxin* Mimics of biological thiols and thiol inhibitors

Book. English.
Published San Diego: Academic Press, 1995

Available at O'Reilly Library.

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    950921726 Main Collection 572.7 3 Weeks Available Part B/Vol. 252


Statement of responsibility: edited by Lester Packer. Part B, Glutathione and thioredoxin, thiols in signal transduction and gene regulation
ISBN: 0121821536, 9780121821531
Note: Includes bibliographical references and indexes.
Physical Description: xxix, 382 p : ill. ; 24 cm.
Subject: Thioredoxin.; Thiols.; Genetic regulation.; Glutathione.; Cellular signal transduction.
Added Entry: Glutathione and thioredoxin, thiols in signal transduction and gene regulation; Biothiols; Glutathione and thioredoxin, thiols in signal transduction and gene regulation.


  1. Glutathione: Distribution, Biosynthesis, Metabolism, and Transport
  2. D.P. Jones, Glutathione Distribution in Natural Products: Absorption and Tissue Distribution.
  3. L.H. Lash, Intracellular Distribution of Thiols and Disulfides: Assay of Mitochondrial Glutathione Transport.
  4. A. Meister, Glutathione Biosynthesis and Its Inhibition.
  5. W.W. Wells, D.P. Xu, and M.P. Washburn, Glutathione: Dehydroascorbate Oxidoreductases.
  6. F. Ursini, M. Maiorino, R. Brigelius-Flohé, K.D. Aumann, A. Roveri, D. Schomburg, and L. Flohé, Diversity of Glutathione Peroxidases.
  7. D.J. Meyer and B. Ketterer, Purification of Soluble Human Glutathione S-Transferases.
  8. H.J. Forman, M.M. Shi, T. Iwamoto, R.-M. Liu, and T.W. Robinson, Measurement of g-Glutamyl Transpeptidase and g-Glutamylcysteine Synthetase Activities in Cells.
  9. T. Kondo, G.L. Dale, and E. Beutler, Thiol Transport from Human Red Blood Cells.
  10. J.A. Fuchs, Glutathione Mutants.
  11. D.J. Reed, Cystathionine.
  12. T. Meier and R.D. Issels, Promotion of Cyst(e)ine Uptake.
  13. Signal Transduction and Gene Regulation
  14. T.P. Holler and P.B. Hopkins, Ovothiols.
  15. S.R. Hubbard, X-Ray Absorption Spectroscopy Studies of Protein Kinase C.
  16. R. Gopalakrishna, Z.H. Chen, and U. Gundimeda, Modificiations of Cysteine-Rich Regions in Protein Kinase C Induced by Oxidant Tumor Promoters and Enzyme-Specific Inhibitors.
  17. F.J. Romero and J. Romá, Glutathione and Protein Kinase C in Peripheral Nervous Tissues.
  18. A.F.G. Quest, E.S.G. Bardes, W.Q. Xie, E. Willott, R.A. Borchardt, and R.M. Bell, Expression of Protein Kinase Cg Regulatory Domain Elements Containing Cysteine-Rich Zinc-Coordinating Regions as Glutathione S-Transferase Fusion Proteins.
  19. F.J.T. Staal, M.T. Anderson, and L.A. Herzenberg, Redox Regulation of Activation of NF-kB Transcription Factor Complex: Effects of N-Acetycysteine.
  20. Y.J. Suzuki and L. Packer, Redox Regulation of DNA-Protein Interaction by Biothiols.
  21. M. Mizuno and L. Packer, Suppression of Protooncogene C-fos Expression by Antioxidant Dihydrolipoic Acid.
  22. M.S. Patel, N.N. Vettakkoruma-Kankav, and T.-C. Liu, Dihydrolipoamide Dehydrogenase: Activity Assays.
  23. Thioredoxin and Glutaredoxin
  24. A. Holmgren and M. Björnstedt, S. Kumar, and A. Holmgren, Selenite and Selenodiglutathione: Reactions with Thioredoxin Systems.
  25. R.S. Hutchison and D.R. Ort, Measurement of Equilibrium Midpoint Potentials of Thiol/Disulfide Regulatory Groups on Thioredoxin-Activated Chloroplast Enzymes.
  26. J.H. Wong, K. Kobrehel, and B.B. Buchanan, Thioredoxin and Seed Proteins.
  27. J.-P. Jacquot, E. Issakidis, P. Decottignies, M. Lemaire, and M.-M. Myroslawa, Analysis and Manipulation of Target Enzymes for Thioredoxin Control.
  28. K. Schulze-Osthoff, H. Schenk, and W. Dröge, Effects of Thioredoxin on Activation Transcription Factor NF-KB.
  29. M. Russel, Thioredoxin Genetics.
  30. P. Schürmann, Ferredoxin: Thioredoxin System.
  31. A. Holmgren and F. Åslund, Flutaredoxin.
  32. H.J. Dyson, Nuclear Magnetic Resonance of Thioredoxin and Glutaredoxin.
  33. Mimics of Biological Thiols and Thiol Inhibitors
  34. R.S. Glass and T.C. Stadtman, Selenophosphate.
  35. M.-O. Christen, Anethole Dithiolethione: Biochemical Considerations.
  36. M.-O. Christen, L. Fackir, and D. Jore, Use of Linoleic Acid Radiolysis for Assay of Antioxidant Action of Anethole Dithiolethione.
  37. P. Rat, M.-O. Christen, M. Thevenin, J.-M. Warnet, and M. Adolphe, Cold Light Fluorimetry: A Microtritration Technology for Cell Culture to Evaluate Anethole dithiolethione and Other Biothiols.
  38. H. Sies, Ebselen.
  39. N. Sato, S. Iwata, A. Yamauchi, T. Hori, and J. Yodoi, Thiol Compounds and Adult T-Cell Leukemia Virus Infection: A Potential Therapeutic Approach.
  40. Author Index.
  41. Subject Index.


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